Title : The molecular biology of the flavin-containing monooxygenases of man.

Pub. Date : 1995 Apr 28

PMID : 7720101






2 Functional Relationships(s)
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Protein Name
Organism
1 FMO1 and FMO3, expressed in either system, displayed product stereoselectivity in their catalysis of the N-oxidation of the pro-chiral tertiary amines, N-ethyl-N-methylaniline (EMA) and pargyline. Pargyline flavin containing dimethylaniline monoxygenase 1 Homo sapiens
2 But in the case of pargyline, the enzymes displayed opposite stereoselectivity, FMO1 producing solely the (+)-enantiomer and FMO3 predominantly the (-)-enantiomer of the N-oxide. Pargyline flavin containing dimethylaniline monoxygenase 1 Homo sapiens