Pub. Date : 1994 Dec
PMID : 7708812
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The inhibitory action (IC50 5.35 x 10(-8) M) of etodolac on PGE2 biosynthesis in rabbit articular chondrocytes stimulated by interleukin-1 (IL-1) beta was about 1/5 that of indomethacin. | Dinoprostone | interleukin-1 beta | Oryctolagus cuniculus |
| 2 | These results indicate that etodolac is an anti-inflammatory drug which suppress IL-1 beta-stimulated PGE2 biosynthesis in rabbit articular chondrocytes, active oxygen generation and bradykinin formation. | Dinoprostone | interleukin-1 beta | Oryctolagus cuniculus |