Title : Taxol and colchicine increase LPS-induced pro-IL-1 beta production, but do not increase IL-1 beta secretion. A role for microtubules in the regulation of IL-1 beta production.

Pub. Date : 1995 Apr 15

PMID : 7706748






4 Functional Relationships(s)
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1 Taxol and colchicine increase LPS-induced pro-IL-1 beta production, but do not increase IL-1 beta secretion. Colchicine interleukin 1 beta Homo sapiens
2 Taxol and colchicine increase LPS-induced pro-IL-1 beta production, but do not increase IL-1 beta secretion. Colchicine interleukin 1 beta Homo sapiens
3 For example, it is known that taxol and colchicine, two drugs that affect microtubule structure and function, increase LPS-induced IL-1 beta release. Colchicine interleukin 1 beta Homo sapiens
4 These findings indicate that taxol and colchicine increase LPS-induced IL-1 beta release by an increase in the production of the precursor molecule. Colchicine interleukin 1 beta Homo sapiens