Title : Kappa-opioid receptors couple to inwardly rectifying potassium channels when coexpressed by Xenopus oocytes.

Pub. Date : 1995 Mar

PMID : 7700253






2 Functional Relationships(s)
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1 Coinjection of kappa receptor cRNA with cRNA coding for a G protein-linked, inwardly rectifying, K+ channel (GIRK1, or KGA) resulted in oocytes that responded to the kappa agonist U-69593 by activating a large (1.0-1.5-microA) K+ current. U 69593 potassium inwardly rectifying channel subfamily J member 3 L homeolog Xenopus laevis
2 Coinjection of kappa receptor cRNA with cRNA coding for a G protein-linked, inwardly rectifying, K+ channel (GIRK1, or KGA) resulted in oocytes that responded to the kappa agonist U-69593 by activating a large (1.0-1.5-microA) K+ current. U 69593 potassium inwardly rectifying channel subfamily J member 3 L homeolog Xenopus laevis