Title : Potent vitamin D3 analogs: their abilities to enhance transactivation and to bind to the vitamin D3 response element.

Pub. Date : 1995 Mar

PMID : 7700077






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 1,25 dihydroxyvitamin D3 [1,25(OH)2D3] mediates its biological activities through specific binding to the vitamin D3 receptor (VDR) and subsequent association with vitamin D3 responsive elements (VDRE) in genes modulated by 1,25(OH)2D3. Cholecalciferol vitamin D receptor Homo sapiens
2 1,25 dihydroxyvitamin D3 [1,25(OH)2D3] mediates its biological activities through specific binding to the vitamin D3 receptor (VDR) and subsequent association with vitamin D3 responsive elements (VDRE) in genes modulated by 1,25(OH)2D3. Cholecalciferol vitamin D receptor Homo sapiens
3 In contrast, biologically active vitamin D3 compounds (Cmpds HM, C, V) in a dose-dependent fashion enhanced the VDR/RXR (retinoid X receptor)-VDRE retarded band. Cholecalciferol vitamin D receptor Homo sapiens