Title : Effects of Agelenopsis aperta toxins on the N-methyl-D-aspartate receptor: polyamine-like and high-affinity antagonist actions.

Pub. Date : 1993 Jul

PMID : 7687289






1 Functional Relationships(s)
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1 Although alpha-agatoxins can interact at the positive allosteric polyamine site on the NMDA receptor, stimulatory effects produced by this interaction may be masked in functional assays due to a separate action of the toxins as high-affinity, noncompetitive antagonists of the receptor. Polyamines glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis