Title : Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells.

Pub. Date : 1993 Jul 15

PMID : 7686898






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In some circumstances, TNF may use a signal transduction pathway involving hydrolysis of sphingomyelin to ceramide and stimulation of a ceramide-activated protein kinase. Ceramides tumor necrosis factor Homo sapiens
2 The cell-permeable ceramide analogs, C2- and C6-ceramide, which mimic effects of TNF, also induced p42mapk phosphorylation within seconds. Ceramides tumor necrosis factor Homo sapiens
3 The cell-permeable ceramide analogs, C2- and C6-ceramide, which mimic effects of TNF, also induced p42mapk phosphorylation within seconds. Ceramides tumor necrosis factor Homo sapiens