Title : In a concerted action kit ligand and interleukin 3 control the synthesis of serotonin in murine bone marrow-derived mast cells. Up-regulation of GTP cyclohydrolase I and tryptophan 5-monooxygenase activity by the kit ligand.

Pub. Date : 1993 Jun 15

PMID : 7685343






3 Functional Relationships(s)
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Protein Name
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1 In a concerted action kit ligand and interleukin 3 control the synthesis of serotonin in murine bone marrow-derived mast cells. Serotonin kit ligand Mus musculus
2 In consequence, the concerted action of IL-3 and KL on the GTP cyclohydrolase I and the tryptophan 5-monooxygenase reaction enhances the production of serotonin to about 20-fold levels. Serotonin kit ligand Mus musculus
3 Additionally, KL specifically causes the release of about half of total serotonin produced. Serotonin kit ligand Mus musculus