Title : Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1.

Pub. Date : 1993 Jun 1

PMID : 7684420






1 Functional Relationships(s)
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Protein Name
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1 Forskolin plus IBMX selectively inhibits TNF-induced increases in ELAM-1 and VCAM-1 mRNA, indicating that the action of cAMP is to block synthesis of these molecules. 1-Methyl-3-isobutylxanthine tumor necrosis factor Homo sapiens