Title : Ligation of the CD5 or CD28 molecules on resting human T cells induces expression of the early activation antigen CD69 by a calcium- and tyrosine kinase-dependent mechanism.

Pub. Date : 1993 Feb

PMID : 7682535






1 Functional Relationships(s)
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1 Cross-linking of CD5 or CD28 induces an early rise of cytoplasmic free calcium concentration ([Ca2+)]i) and both this rise and CD69 expression were inhibited by chelation of extracellular Ca2+ with ethyleneglycol-bis-(2-aminoethyl)-tetraacetate (EGTA). ethyleneglycol-bis-(2-aminoethyl)-tetraacetate CD28 molecule Homo sapiens