Title : Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes.

Pub. Date : 1993 Apr 1

PMID : 7680961






1 Functional Relationships(s)
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1 Here we show that active (phorbol myristate acetate, phorbol dibutyrate acetate, and mezerein) but not inactive (4 beta-phorbol) tumor-promoting agents inhibit the mAb-induced modulation of CD2 and CD5, but not CD3, without concomitant changes in the surface distribution of these antigens (such as capping). phorbol dibutyrate acetate CD2 molecule Homo sapiens