Title : Molecular basis for the species selectivity of the substance P antagonist CP-96,345.

Pub. Date : 1993 Feb 5

PMID : 7679096






5 Functional Relationships(s)
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1 Molecular basis for the species selectivity of the substance P antagonist CP-96,345. CP96 tachykinin precursor 1 Homo sapiens
2 The non-peptide substance P (SP) antagonist CP-96,345 has a 90-fold selectivity for the human neurokinin-1 (NK-1) or SP receptor over the rat NK-1 receptor, while the agonist SP shows no such selectivity. CP96 tachykinin precursor 1 Homo sapiens
3 The non-peptide substance P (SP) antagonist CP-96,345 has a 90-fold selectivity for the human neurokinin-1 (NK-1) or SP receptor over the rat NK-1 receptor, while the agonist SP shows no such selectivity. CP96 tachykinin precursor 1 Homo sapiens
4 The non-peptide substance P (SP) antagonist CP-96,345 has a 90-fold selectivity for the human neurokinin-1 (NK-1) or SP receptor over the rat NK-1 receptor, while the agonist SP shows no such selectivity. CP96 tachykinin precursor 1 Homo sapiens
5 The non-peptide substance P (SP) antagonist CP-96,345 has a 90-fold selectivity for the human neurokinin-1 (NK-1) or SP receptor over the rat NK-1 receptor, while the agonist SP shows no such selectivity. CP96 tachykinin precursor 1 Homo sapiens