Pub. Date : 1995 Sep 15
PMID : 7662974
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Although the induction of synthesis and early accumulation of cyclin E and cyclin E-associated kinase activity appeared normal, the appearance of cyclin A and cyclin A-associated kinase activity were inhibited by DFO. | Deferoxamine | cyclin A2 | Homo sapiens | ||
2 | Although the induction of synthesis and early accumulation of cyclin E and cyclin E-associated kinase activity appeared normal, the appearance of cyclin A and cyclin A-associated kinase activity were inhibited by DFO. | Deferoxamine | cyclin A2 | Homo sapiens | ||
3 | However, the production of cyclin A mRNA appeared to be normal in the presence of DFO. | Deferoxamine | cyclin A2 | Homo sapiens | ||
4 | A major effect of DFO in blocking cell cycle progression may be mediated through inhibition of the appearance of cyclin A protein and, therefore, a major component of p33cdk2 activity. | Deferoxamine | cyclin A2 | Homo sapiens |