Title : DNA cleavage in rat liver nuclei activated by Mg2+ or Ca2+ + Mg2+ is inhibited by a variety of structurally unrelated inhibitors.

Pub. Date : 1994 Nov-Dec

PMID : 7654337






1 Functional Relationships(s)
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1 Furthermore, we show that the heavy metals Cd2+ and Hg2+, dichloroisocoumarin (a general serine protease inhibitor), and N-ethyl maleimide (NEM, a specific thiol reagent) are potent inhibitors of both the Mg(2+)- and Ca2+/Mg(2+)-stimulated DNA fragmentation. Mercuric cation Serine protease inhibitor Rattus norvegicus