Title : Addition of hTNF alpha potentiates cytotoxicity of taxol in human ovarian cancer lines.

Pub. Date : 1995 May-Jun

PMID : 7645972






4 Functional Relationships(s)
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1 Addition of hTNF alpha potentiates cytotoxicity of taxol in human ovarian cancer lines. Paclitaxel tumor necrosis factor Homo sapiens
2 We observed that the combination of low concentration of hTNF alpha with taxol could increase the cytotoxic activity of taxol in SKOV3 cells. Paclitaxel tumor necrosis factor Homo sapiens
3 Furthermore, a four-hour pretreatment with taxol before adding hTNF alpha to the culture has shown a significant increase in their cytotoxic activity. Paclitaxel tumor necrosis factor Homo sapiens
4 This indicates that taxol could alter the mechanism of hTNF alpha-resistance. Paclitaxel tumor necrosis factor Homo sapiens