Title : Inhibition of proteinase 3 by ANCA and its correlation with disease activity in Wegener's granulomatosis.

Pub. Date : 1995 Jun

PMID : 7643521






1 Functional Relationships(s)
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1 We purified IgG from 21 PR3-ANCA positive sera obtained from 17 patients with WG, and determined its effect on the esterolytic and proteolytic activity of purified human PR3 using Boc-Ala-O-Nitrophenyl ester and fluoresceinated-elastin as enzyme substrates. fluoresceinated proteinase 3 Homo sapiens