Title : Block of the N-methyl-D-aspartate receptor by phencyclidine-like drugs is influenced by alternative splicing.

Pub. Date : 1995 May 12

PMID : 7637880






5 Functional Relationships(s)
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Protein Name
Organism
1 The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assembled from NMDAR1 subunits lacking this insert (NR1(011) and NR1(001)). Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assembled from NMDAR1 subunits lacking this insert (NR1(011) and NR1(001)). Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
3 The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assembled from NMDAR1 subunits lacking this insert (NR1(011) and NR1(001)). Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
4 The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assembled from NMDAR1 subunits lacking this insert (NR1(011) and NR1(001)). Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
5 The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assembled from NMDAR1 subunits lacking this insert (NR1(011) and NR1(001)). Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis