Pub. Date : 1995 Mar
PMID : 7630488
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg(2+)-insensitive mutants. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 2 | In the current study, dimeric and trimeric combinations of N-methyl-D-aspartate (NMDA) receptor subunits were expressed in Xenopus oocytes and their sensitivity to ethanol was examined using conventional two electrode voltage clamp methods. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 3 | In oocytes expressing the NR1/2A subunits, ethanol (25, 50 and 100 mM) inhibited NMDA (100 microM)/glycine (10 microM) induced currents by 21, 31 and 47%; respectively. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 4 | Ethanol inhibition of NMDA-stimulated currents in oocytes injected with NR1/2A/2B or NR1/2A/2C was not significantly different from that observed in NR1/2B or NR1/2C injected oocytes, respectively. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 5 | Ethanol inhibition of NMDA-stimulated currents in oocytes injected with NR1/2A/2B or NR1/2A/2C was not significantly different from that observed in NR1/2B or NR1/2C injected oocytes, respectively. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |
| 6 | Ethanol inhibition of NMDA-stimulated currents in oocytes injected with NR1/2A/2B or NR1/2A/2C was not significantly different from that observed in NR1/2B or NR1/2C injected oocytes, respectively. | Ethanol | glutamate ionotropic receptor NMDA type subunit 1 L homeolog | Xenopus laevis |