Title : Inhibition by interleukin-1 beta of noradrenaline release in rat spleen: involvement of lymphocytes, NO and opioid receptors.

Pub. Date : 1995 Apr

PMID : 7630433






3 Functional Relationships(s)
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1 Inhibition by interleukin-1 beta of noradrenaline release in rat spleen: involvement of lymphocytes, NO and opioid receptors. Norepinephrine interleukin 1 beta Rattus norvegicus
2 Effects of indomethacin, N omega-nitro-L-arginine (NNA) and naloxone, and of pretreatment with cyclophosphamide (CY), on the interleukin (IL)-1 beta induced inhibition of exocytotic noradrenaline release were investigated in the isolated, vascularly perfused spleen of the rat. Norepinephrine interleukin 1 beta Rattus norvegicus
3 Perfusion of the spleen with Tyrode"s solution containing IL-1 beta (100 pg/ml) for 90 min caused an inhibition of the stimulation-evoked noradrenaline overflow which persisted for at least 20 min after washout of the IL. Norepinephrine interleukin 1 beta Rattus norvegicus