Pub. Date : 1995 Mar
PMID : 7628292
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, expressed human UGT1.4 protein exhibited glucuronidation activity toward tertiary amine substrates, such as imipramine, cyproheptadine, tripelennamine, and chlorpromazine, which form quaternary ammonium-linked glucuronides. | Amines | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
2 | Although a number of other UGT gene products are capable of catalyzing the glucuronidation of primary amine substrates, expressed human UGT1.4 protein is the only UGT isoform that has been shown to conjugate tertiary amine substrates, forming quaternary ammonium-linked glucuronides. | Amines | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
3 | Although a number of other UGT gene products are capable of catalyzing the glucuronidation of primary amine substrates, expressed human UGT1.4 protein is the only UGT isoform that has been shown to conjugate tertiary amine substrates, forming quaternary ammonium-linked glucuronides. | Amines | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |