Pub. Date : 1995 Aug 1
PMID : 7620184
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | As compared with the patients with no cytogenetic response, the patients with any cytogenetic response (complete, partial or minor) after the IFN-alpha or busulfan treatment were significantly superior in the duration of chronic phase (IFN-alpha group; P = .0017, busulfan group; P = .0010) even after correction for the time to response using the landmark analysis. | Busulfan | interferon alpha 1 | Homo sapiens | ||
2 | As compared with the patients with no cytogenetic response, the patients with any cytogenetic response (complete, partial or minor) after the IFN-alpha or busulfan treatment were significantly superior in the duration of chronic phase (IFN-alpha group; P = .0017, busulfan group; P = .0010) even after correction for the time to response using the landmark analysis. | Busulfan | interferon alpha 1 | Homo sapiens | ||
3 | These results demonstrate that IFN-alpha treatment produces a significantly superior cytogenetic response and survival rate as compared with the busulfan treatment, and unexpectedly, that busulfan can also eliminate Philadelphia chromosome positive clone in a few patients who showed prolonged survival rate and duration of chronic phase. | Busulfan | interferon alpha 1 | Homo sapiens |