Title : PYY in brain stem nuclei induces vagal stimulation of gastric acid secretion in rats.

Pub. Date : 1995 Jun

PMID : 7611415






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PYY (30-200 ng) microinjected into the dorsal motor nucleus of the vagus (DMN) induces a dose-related and vagal-dependent stimulation of GAS (net increase from 13 +/- 4 to 59 +/- 12 mumol/90 min). Dimethylnitrosamine peptide YY Rattus norvegicus
2 GAS induced by PYY into the DMN was potentiated by coinjection of thyrotropin-releasing hormone (TRH, 30 ng) or the serotonin receptor (5-HT2) agonist (+/-)-1-(4-methyl-1-piperazinyl)-pyrrolo(1,2-a)quinoxaline (357 ng) and by microinjection of kainic acid (1 ng) into the raphe pallidus. Dimethylnitrosamine peptide YY Rattus norvegicus