Title : Cloning and stable expression of a cDNA encoding a rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin.

Pub. Date : 1995 Jun

PMID : 7603447






3 Functional Relationships(s)
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1 Cloning and stable expression of a cDNA encoding a rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin. Bilirubin UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus
2 The deduced amino acid sequence of pM1 contains amino acid sequences identical to the amino-terminal and internal peptides of the purified rat liver opioid UGT and to sequences reported for a rat liver bilirubin UGT [FEBS Lett. Bilirubin UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus
3 These results show that bilirubin and opioids can be conjugated by the same rat liver UGT. Bilirubin UDP glycosyltransferase 2 family, polypeptide B Rattus norvegicus