Title : Post-transcriptional stabilization of urokinase plasminogen activator mRNA by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a human keratinocyte cell line.

Pub. Date : 1995 Jul

PMID : 7597708






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Genes altered by TCDD at the transcriptional level in the transformed human keratinocyte cell line SCC-12F include cytochrome P4501A1 (CYP1A1), CYP1B1, transforming growth factor-beta 2, and plasminogen activator inhibitor-2 (PAI-2). Polychlorinated Dibenzodioxins serpin family B member 2 Homo sapiens
2 Genes altered by TCDD at the transcriptional level in the transformed human keratinocyte cell line SCC-12F include cytochrome P4501A1 (CYP1A1), CYP1B1, transforming growth factor-beta 2, and plasminogen activator inhibitor-2 (PAI-2). Polychlorinated Dibenzodioxins serpin family B member 2 Homo sapiens
3 We report that in addition to the transcriptional induction of PAI-2, treatment of SCC-12F cells with 10 nM TCDD also resulted in an increase in urokinase-plasminogen activator (u-PA) mRNA. Polychlorinated Dibenzodioxins serpin family B member 2 Homo sapiens