Pub. Date : 1995 Jul
PMID : 7595067
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of low density lipoprotein receptor gene expression in HepG2 and Caco2 cells by palmitate, oleate, and 25-hydroxycholesterol. | 25-hydroxycholesterol | low density lipoprotein receptor | Homo sapiens |
| 2 | The suppressive effect of 25-hydroxycholesterol on LDL-receptor regulation was studied by incubating HepG2 and Caco2 cells grown either in 10% FCS or 10% LPDS for 24 h and then for 0-24 h with various doses of 25-hydroxycholesterol. | 25-hydroxycholesterol | low density lipoprotein receptor | Homo sapiens |
| 3 | The combination of palmitate (0.8 mM) and 25-hydroxycholesterol (2.5-5 micrograms/ml) suppressed LDL-receptor activity by 65% in HepG2 cells and by 52% in Caco2 cells. | 25-hydroxycholesterol | low density lipoprotein receptor | Homo sapiens |