Title : Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells.

Pub. Date : 1995 Oct 27

PMID : 7592779






6 Functional Relationships(s)
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Protein Name
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1 Stimulation of NIH 3T3 cells with platelet-derived growth factor (PDGF)-BB and 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances vascular endothelial growth factor (VEGF) gene expression. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus
2 Stimulation of NIH 3T3 cells with platelet-derived growth factor (PDGF)-BB and 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances vascular endothelial growth factor (VEGF) gene expression. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus
3 Stimulation of NIH 3T3 cells with platelet-derived growth factor (PDGF)-BB and 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances vascular endothelial growth factor (VEGF) gene expression. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus
4 Stimulation of NIH 3T3 cells with platelet-derived growth factor (PDGF)-BB and 12-O-tetradecanoylphorbol-13-acetate (TPA) enhances vascular endothelial growth factor (VEGF) gene expression. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus
5 To address the question of whether Ras and Raf are involved in the induction of VEGF gene expression by PDGF and TPA, we examined the effects of both factors on NIH 3T3 cells stably transfected with v-Ha-ras or v-raf. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus
6 Stimulation with PDGF or TPA resulted in increased VEGF mRNA in all cell lines, with highest levels found in the transformed cells. Tetradecanoylphorbol Acetate vascular endothelial growth factor A Mus musculus