Title : Modification of tumor necrosis factor-alpha (TNF-alpha) production by the Na(+)-dependent HCO3- cotransport in lipopolysaccharide-activated human monocytes.

Pub. Date : 1995 Jun

PMID : 7591712






1 Functional Relationships(s)
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1 The amiloride analog 5-(N-ethyl-N-isopropyl)amiloride (EIPA), an inhibitor of the Na+/H+ antiporter, inhibited TNF-alpha production with an EC50 of 3.3 microM. Amiloride tumor necrosis factor Homo sapiens