Title : Effect of sulfated xylans during the interaction of [125I]-thrombin with antithrombin III or heparin cofactor II of human plasma.

Pub. Date : 1995 Jan-Mar

PMID : 7588997






3 Functional Relationships(s)
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1 Addition of OSXS or SP-54 enhanced the complexation of thrombin with HC-II or with both AT-III and HC-II depending upon the concentration and the duration of the interactions of the sulfated compounds with plasma. Pentosan Sulfuric Polyester serpin family C member 1 Homo sapiens
2 During the 30 s interaction, OSXS and SP-54 enhanced both AT-III-thrombin and HC-II-thrombin interaction while heparin was more selective and enhanced only the AT-III-thrombin interaction. Pentosan Sulfuric Polyester serpin family C member 1 Homo sapiens
3 The complexations of AT-III-thrombin and HC-II-thrombin were reversed in the presence of 200 micrograms/ml of SP-54 during a 30 s interaction or in presence of 100 micrograms/ml of OSXS during a 2 min interaction. Pentosan Sulfuric Polyester serpin family C member 1 Homo sapiens