Title : Characterization of rat GLUT5 and functional analysis of chimeric proteins of GLUT1 glucose transporter and GLUT5 fructose transporter.

Pub. Date : 1995 Nov

PMID : 7588216






4 Functional Relationships(s)
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1 Rat GLUT5 was exclusively targeted to the plasma membrane and exhibited a transport activity, not for glucose, but for fructose. Fructose solute carrier family 2 member 5 Rattus norvegicus
2 Next, to investigate the domains required for transport of glucose/fructose in GLUT1 and/or GLUT5, several chimeric GLUT1/GLUT5 proteins were expressed, and their glucose and/or fructose transport activities were studied. Fructose solute carrier family 2 member 5 Rattus norvegicus
3 In conclusion, GLUT5 is a transporter exclusively for fructose and the structural requirements for fructose transport are more stringent than those for glucose transport among hexose transporter proteins. Fructose solute carrier family 2 member 5 Rattus norvegicus
4 In conclusion, GLUT5 is a transporter exclusively for fructose and the structural requirements for fructose transport are more stringent than those for glucose transport among hexose transporter proteins. Fructose solute carrier family 2 member 5 Rattus norvegicus