Title : Growth hormone (GH)-induced tyrosine-phosphorylated proteins in cells that express GH receptors.

Pub. Date : 1995 Summer

PMID : 7580939






15 Functional Relationships(s)
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1 Growth hormone (GH)-induced tyrosine-phosphorylated proteins in cells that express GH receptors. Tyrosine growth hormone Mus musculus
2 Growth hormone (GH)-induced tyrosine-phosphorylated proteins in cells that express GH receptors. Tyrosine growth hormone Mus musculus
3 We have shown previously that growth hormone (GH)-induced tyrosine phosphorylation of a 95-kDa protein in mouse L-cells stably transfected with the GH receptor. Tyrosine growth hormone Mus musculus
4 We have shown previously that growth hormone (GH)-induced tyrosine phosphorylation of a 95-kDa protein in mouse L-cells stably transfected with the GH receptor. Tyrosine growth hormone Mus musculus
5 In addition to induction of pp95, we have established that GH also induces tyrosine phosphorylation of a 42-kDa protein and a 130-kDa protein, as detected with phosphotyrosine antibodies. Tyrosine growth hormone Mus musculus
6 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
7 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
8 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
9 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
10 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
11 A time course of tyrosine phosphorylation on GH treatment indicates that within the GH signal transduction cascade, tyrosine phosphorylation of pp95 occurs by 1 min, whereas tyrosine phosphorylation of pp42 was not detected until 5 min. Tyrosine growth hormone Mus musculus
12 Additionally, the concentration of GH needed to stimulate tyrosine phosphorylation of pp42 was greater than that required for pp95. Tyrosine growth hormone Mus musculus
13 These results suggest that GH induction of tyrosine-phosphorylated pp42 may represent a common signal transduction point of various growth factors, including GH, whereas tyrosine phosphorylation of pp95 is GH specific. Tyrosine growth hormone Mus musculus
14 These results suggest that GH induction of tyrosine-phosphorylated pp42 may represent a common signal transduction point of various growth factors, including GH, whereas tyrosine phosphorylation of pp95 is GH specific. Tyrosine growth hormone Mus musculus
15 These results suggest that GH induction of tyrosine-phosphorylated pp42 may represent a common signal transduction point of various growth factors, including GH, whereas tyrosine phosphorylation of pp95 is GH specific. Tyrosine growth hormone Mus musculus