Title : Regulation of yeast phospholipid biosynthetic gene expression in response to inositol involves two superimposed mechanisms.

Pub. Date : 1995 Oct 10

PMID : 7568205






4 Functional Relationships(s)
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1 We have previously suggested that this response to inositol may be dictated by regulating transcription of the cognate activator gene, INO2. Inositol Ino2p Saccharomyces cerevisiae S288C
2 These observations suggested that the response to inositol may involve both regulation of INO2 transcription as well as OPI1-mediated repression. Inositol Ino2p Saccharomyces cerevisiae S288C
3 We investigated these possibilities by examining the effect of inositol on target gene expression in a strain containing the INO2 gene under control of the GAL1 promoter. Inositol Ino2p Saccharomyces cerevisiae S288C
4 Furthermore, the effect of inositol on target gene expression was eliminated by deleting the OPI1 gene in the GAL1-INO2-containing strain. Inositol Ino2p Saccharomyces cerevisiae S288C