Pub. Date : 1995 Sep
PMID : 7564475
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Augmentation by aphidicolin of 1-beta-D-arabinofuranosylcytosine-induced c-jun and NF-kappa B activation in a human myeloid leukemia cell line: correlation with apoptosis. | Aphidicolin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens | ||
2 | Although aphidicolin itself had a marginal effect on c-jun expression, it significantly augmented ara-C induced c-jun upregulation by shortening the lag time and lowering ara-C concentrations necessary for the induction of detectable c-jun transcripts. | Aphidicolin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens | ||
3 | Although aphidicolin itself had a marginal effect on c-jun expression, it significantly augmented ara-C induced c-jun upregulation by shortening the lag time and lowering ara-C concentrations necessary for the induction of detectable c-jun transcripts. | Aphidicolin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens | ||
4 | Thus, the activation of NF-kappa B and c-jun expression seems to be well correlated with the potentiation by aphidicolin of ara-C-induced apoptosis. | Aphidicolin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |