Title : Flavinylation of monoamine oxidase B.

Pub. Date : 1995 Oct 6

PMID : 7559533






4 Functional Relationships(s)
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1 We found that MAO B is expressed equally in the presence or absence of FAD and that apoMAO B can be inserted into the outer mitochondrial membrane. Flavin-Adenine Dinucleotide monoamine oxidase B Homo sapiens
2 Since the addition of riboflavin, FMN, or FAD resulted in equal levels of MAO B activity, we conclude that the flavin which initially binds to apoMAO B is FAD. Flavin-Adenine Dinucleotide monoamine oxidase B Homo sapiens
3 Since the addition of riboflavin, FMN, or FAD resulted in equal levels of MAO B activity, we conclude that the flavin which initially binds to apoMAO B is FAD. Flavin-Adenine Dinucleotide monoamine oxidase B Homo sapiens
4 Thus, FAD binds to MAO B in a dual manner at Glu34 noncovalently and Cys397 covalently. Flavin-Adenine Dinucleotide monoamine oxidase B Homo sapiens