Title : Regulation of CD45 engagement by the B-cell receptor CD22.

Pub. Date : 1995 Apr 25

PMID : 7537381






3 Functional Relationships(s)
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1 The B-cell receptor CD22 binds sialic acid linked alpha-2-6 to terminal galactose residues on N-linked oligosaccharides associated with several cell-surface glycoproteins. N-Acetylneuraminic Acid CD22 molecule Homo sapiens
2 We also show that addition of sialic acid by beta-galactoside alpha-2,6-sialyltransferase to the CD22 molecule abrogates interactions between CD22 and its ligands. N-Acetylneuraminic Acid CD22 molecule Homo sapiens
3 We also show that addition of sialic acid by beta-galactoside alpha-2,6-sialyltransferase to the CD22 molecule abrogates interactions between CD22 and its ligands. N-Acetylneuraminic Acid CD22 molecule Homo sapiens