Title : Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.

Pub. Date : 1995 Mar 31

PMID : 7535773






3 Functional Relationships(s)
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Protein Name
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1 Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens
2 Human GH was shown to promote the rapid tyrosyl phosphorylation of 66-, 52-, and 46-kDa SHC proteins in 3T3-F442A fibroblasts. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens
3 These findings suggest that GH stimulates: 1) the association of SHC proteins with JAK2.GHR complexes via the SHC-SH2 domain, 2) tyrosyl phosphorylation of SHC proteins, and 3) subsequent Grb2 association with SHC proteins. cyclo(tyrosyl-tyrosyl) growth hormone 1 Homo sapiens