Pub. Date : 1995 Mar 31
PMID : 7535773
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2. | cyclo(tyrosyl-tyrosyl) | growth hormone 1 | Homo sapiens |
2 | Human GH was shown to promote the rapid tyrosyl phosphorylation of 66-, 52-, and 46-kDa SHC proteins in 3T3-F442A fibroblasts. | cyclo(tyrosyl-tyrosyl) | growth hormone 1 | Homo sapiens |
3 | These findings suggest that GH stimulates: 1) the association of SHC proteins with JAK2.GHR complexes via the SHC-SH2 domain, 2) tyrosyl phosphorylation of SHC proteins, and 3) subsequent Grb2 association with SHC proteins. | cyclo(tyrosyl-tyrosyl) | growth hormone 1 | Homo sapiens |