Title : Regulation of c-fos expression by convulsants and hexachlorocyclohexane isomers in primary cultures of cortical neurons.

Pub. Date : 1995 Apr

PMID : 7534335






6 Functional Relationships(s)
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1 Regulation of c-fos expression by convulsants and hexachlorocyclohexane isomers in primary cultures of cortical neurons. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Lindane (gamma-hexachlorocyclohexane), Bay K 8644, pentylenetetrazole, and picrotoxinin produced a significant increase in c-fos immunoreactivity and in c-fos mRNA expression. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 Lindane (gamma-hexachlorocyclohexane), Bay K 8644, pentylenetetrazole, and picrotoxinin produced a significant increase in c-fos immunoreactivity and in c-fos mRNA expression. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
4 Lindane (gamma-hexachlorocyclohexane), Bay K 8644, pentylenetetrazole, and picrotoxinin produced a significant increase in c-fos immunoreactivity and in c-fos mRNA expression. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
5 Lindane (gamma-hexachlorocyclohexane), Bay K 8644, pentylenetetrazole, and picrotoxinin produced a significant increase in c-fos immunoreactivity and in c-fos mRNA expression. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens
6 The results obtained with delta-hexachlorocyclohexane and nifedipine suggest that picrotoxinin activates c-fos expression by calcium-requiring intracellular signaling pathways that are different from those activated by Bay K 8644, pentylenetetrazole, or gamma-hexachlorocyclohexane, which, at least in part, act via L-type calcium channels. Hexachlorocyclohexane Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens