Title : Subtype- and species-selectivity of a tachykinin receptor antagonist, FK888, for cloned rat and human tachykinin receptors.

Pub. Date : 1994 Oct 14

PMID : 7531648






1 Functional Relationships(s)
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1 In Chinese hamster ovary cells permanently expressing the human NK1 receptor, FK888 inhibited the substance P-induced phosphatidylinositol hydrolysis and produced a parallel shift in the dose-response curve for substance P. Phosphatidylinositols tachykinin precursor 1 Homo sapiens