Title : Three distinct messenger RNAs can encode the human immunosuppressant-binding protein FKBP12.

Pub. Date : 1994 Dec 15

PMID : 7529739






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 FKBP12 is an 11.8-kDa protein that binds the potent immunosuppressants FK506 and rapamycin. Tacrolimus FKBP prolyl isomerase 1A pseudogene 4 Homo sapiens
2 When bound to FK506, FKBP12 forms an inhibitory complex with calcineurin and interferes with signal transduction in activated T lymphocytes. Tacrolimus FKBP prolyl isomerase 1A pseudogene 4 Homo sapiens