Title : Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries.

Pub. Date : 1994 May

PMID : 7521457






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bradykinin increased [Ca2+]i, and this action was antagonized by the B2 kinin receptor antagonist Hoe 140 and the K channel inhibitor tetrabutylammonium (TBA). tetrabutylammonium kininogen 1 Bos taurus
2 Bradykinin increased [Ca2+]i, and this action was antagonized by the B2 kinin receptor antagonist Hoe 140 and the K channel inhibitor tetrabutylammonium (TBA). tetrabutylammonium kininogen 1 Bos taurus
3 The results indicate that the bradykinin response is mediated by biosynthesis of EDRF, which is sensitive to L-NNA, and of EDHF, which is sensitive to TBA. tetrabutylammonium kininogen 1 Bos taurus