Title : The folding of bovine pancreatic trypsin inhibitor in the Escherichia coli periplasm.

Pub. Date : 1994 Aug 19

PMID : 7520437






2 Functional Relationships(s)
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Protein Name
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1 In vivo, native BPTI formed with a half-life of 7 min which is 3-fold faster than the optimal in vitro folding rate in growth media supplemented with low molecular weight disulfides. Disulfides spleen trypsin inhibitor I Bos taurus
2 We found that the folding of BPTI in E. coli was absolutely dependent on DsbA, a protein which accelerates the formation of disulfide bonds in the periplasm. Disulfides spleen trypsin inhibitor I Bos taurus