Pub. Date : 1994 Sep 1
PMID : 7519646
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This study investigates the ability of the experimental drug suramin to block the activation of HUVEC by endotoxin and by the proinflammatory cytokines IL-1 and TNF. | Suramin | interleukin 1 beta | Homo sapiens |
2 | We demonstrate that the inducible expression of several adhesion molecules by LPS and IL-1 beta but not by TNF-alpha is prevented by suramin. | Suramin | interleukin 1 beta | Homo sapiens |
3 | In a dose-dependent manner, suramin inhibits the binding of neutrophils and T lymphocytes to LPS and IL-1 beta but not to TNF-alpha-activated HUVEC. | Suramin | interleukin 1 beta | Homo sapiens |