Pub. Date : 1994 Jul 29
PMID : 7518460
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 2 | In vitro, the tyrosine-phosphorylated PTP1C underwent rapid auto-dephosphorylation, an effect which could be blocked by the addition of sodium vanadate. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 3 | The sites of tyrosine phosphorylation were characterized from purified enzyme following treatment with insulin receptor kinase and from PTP1C expressed in 293 cells which had been stimulated with platelet-derived growth factor. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |
| 4 | This result was confirmed in vivo through site-specific mutagenesis of PTP1C expressed in 293 cells; changing Tyr538 to Phe538 completely abolished tyrosine phosphorylation of the molecule. | Tyrosine | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |