Title : Hyaluronate is costimulatory for human T cell effector functions and binds to CD44 on activated T cells.

Pub. Date : 1994 Jul 1

PMID : 7515923






1 Functional Relationships(s)
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1 Here, we show that hyaluronate (HA), a CD44 ligand, in conjunction with CD3/TCR-mediated stimuli, is costimulatory for human peripheral blood T cell proliferation, for IL-2 production by Th clones, and for release of trypsin-like esterase by cytolytic T cell clones. ha interleukin 2 Homo sapiens