Title : Conformational change in antithrombin induced by heparin probed with a monoclonal antibody against the 1C/4B region.

Pub. Date : 1994 Apr 12

PMID : 7512382






1 Functional Relationships(s)
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1 However, interaction of the MAb with antithrombin was reduced by several substitution mutations (Phe402-->Cys, Phe402-->Ser, Phe402-->Leu, Ala404-->Thr, Pro407-->Thr) in the 402-407 sequence which codes for amino acid residues of strand 1C and the polypeptide leading to strand 4B. Cysteine serpin family C member 1 Homo sapiens