Title : Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor.

Pub. Date : 1994 Jan

PMID : 7510997






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 A recombinant p59/HBI-glutathione-S-transferase fusion protein, purified by Sephadex LH-20 filtration of tritiated drug-p59/HBI complexes, binds FK506 and RAP with apparent Kd values of 75 +/- 40 and 40 +/- 15 nM, respectively. Tacrolimus FKBP prolyl isomerase 4 Homo sapiens
2 Purification of cytosol PR on immobilized FK506 yields a 9S form still containing hsp90, hsp70 and p59/HBI associated to PR units. Tacrolimus FKBP prolyl isomerase 4 Homo sapiens