Title : Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.

Pub. Date : 1994 Feb 15

PMID : 7509602






1 Functional Relationships(s)
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1 Stimulation with cytomix, a combination of interleukin-1 beta, tumor necrosis factor-alpha, and interferon-gamma, elevated nitrite levels by 873% in the culture supernatants and enhanced the conversion of arginine to citrulline by 273% at 24 h. An increased number of cells stained for iNOS and an increase in iNOS mRNA was also observed. Arginine interferon gamma Mus musculus