Title : Bacterial lipoproteins may substitute for cytokines in the humoral immune response to T cell-independent type II antigens.

Pub. Date : 1995 Dec 15

PMID : 7499841






2 Functional Relationships(s)
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1 However, when combined with a multivalent membrane (m)Ig-mediated cross-linking signal, dextran-conjugated anti-IgD Abs (alpha delta-dex), lipoproteins mediate up to 10,000-fold inductions in IgM secretion and up to 25-fold enhancements in cellular proliferation relative to that observed with alpha delta-dex alone, in the absence of added cytokines. alpha delta-dex chemokine (C-X-C motif) ligand 9 Mus musculus
2 However, when combined with a multivalent membrane (m)Ig-mediated cross-linking signal, dextran-conjugated anti-IgD Abs (alpha delta-dex), lipoproteins mediate up to 10,000-fold inductions in IgM secretion and up to 25-fold enhancements in cellular proliferation relative to that observed with alpha delta-dex alone, in the absence of added cytokines. alpha delta-dex chemokine (C-X-C motif) ligand 9 Mus musculus