Title : Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse.

Pub. Date : 1995 Jul

PMID : 7494796






3 Functional Relationships(s)
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Protein Name
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1 The area under the plasma level-time curve increased 6 fold when doxorubicin was administered in niosomes, compared to doxorubicin solution (66.0 micrograms.h mL-1 and 10.3 micrograms. Doxorubicin L1 cell adhesion molecule Mus musculus
2 The area under the tumour level time curve was increased by over 50% by the administration of doxorubicin in niosomes when compared to the drug administered in solution (58.6 micrograms.h mL-1 and 34.3 micrograms.h mL-1, respectively). Doxorubicin L1 cell adhesion molecule Mus musculus
3 The area under the tumour level time curve was increased by over 50% by the administration of doxorubicin in niosomes when compared to the drug administered in solution (58.6 micrograms.h mL-1 and 34.3 micrograms.h mL-1, respectively). Doxorubicin L1 cell adhesion molecule Mus musculus