Title : Induction of the synthesis of hsp27 and alpha B crystallin in tissues of heat-stressed rats and its suppression by ethanol or an alpha 1-adrenergic antagonist.

Pub. Date : 1995 Jun

PMID : 7490266






2 Functional Relationships(s)
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1 Accumulation of hsp70 after heat stress, at least in the liver, was inhibited by ethanol or prazosin in a similar manner to that of hsp27, as detected on Western blot analysis. Prazosin heat shock protein family A (Hsp70) member 1B Rattus norvegicus
2 These results suggest that the induction of hsp27 and alpha B crystallin, as well as of hsp70, in tissues of heat-stressed rats is controlled by a physiological process(es) that is sensitive to ethanol and prazosin, and is operative for a short time during the application of heat stress. Prazosin heat shock protein family A (Hsp70) member 1B Rattus norvegicus