Pub. Date : 1980 Dec
PMID : 7449252
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of angiotensin II and noradrenaline in lowering renal blood flow was reduced during renal arterial infusion of either bradykinin (10 ng min-1 kg-1) or prostaglandin E2 (4 ng min-1 kg-1). | Norepinephrine | kininogen 1 | Canis lupus familiaris |
| 2 | Pretreatment of the dogs with an inhibitor of prostaglandin synthesis, sodium meclofenamate (5 mg/kg), blunted the inhibitory action of bradykinin, but not that of prostaglandin E2, on renal vascular reactivity to angiotensin II and noradrenaline. | Norepinephrine | kininogen 1 | Canis lupus familiaris |
| 3 | These results indicate that bradykinin reduces the renal vasoconstriction induced by angiotensin II and noradrenaline in the dog by a mechanism dependent upon synthesis of prostaglandins. | Norepinephrine | kininogen 1 | Canis lupus familiaris |